Notice: Function _load_textdomain_just_in_time was called incorrectly. Translation loading for the wordpress-seo domain was triggered too early. This is usually an indicator for some code in the plugin or theme running too early. Translations should be loaded at the init action or later. Please see Debugging in WordPress for more information. (This message was added in version 6.7.0.) in /var/www/html/wp-includes/functions.php on line 6260 The Basics About Excipients | Contract Pharma

What are you searching for?

Sign in
Online Exclusives

The Basics About Excipients

The purpose of an inactive ingredient and supporting the manufacturing process for the delivery of the active substance.

Author Image

By: Kristin Brooks

Managing Editor, Contract Pharma

An excipient is an ingredient intentionally added to the formulation of a dosage form other than the active substance or active pharmaceutical ingredient (API). Although excipients are not necessarily inert, the term is often synonymous with inactive ingredient.
 
An inactive substance serves as the vehicle for a drug or other active substance and can include coloring agents, preservatives, and fillers.
 
Excipients can also be used in the manufacturing process to support the delivery of the active substance by aiding in vitro stability to support expected shelf life.
 
An excipient formulated with the active ingredient of a medication can be used for long-term stabilization, bulking up solid formulations that contain small amounts of potent active ingredients, or to enhance the active ingredient in the final dosage form, such as facilitating drug absorption, reducing viscosity, or enhancing solubility.
 
Leveraging appropriate excipients also depends on drug delivery and the dosage form, as well as the active ingredient among other factors.
 
Excipients were once inactive ingredients, but now can be a key determinant of dosage form based on pharmacodynamics (PD) and pharmacokinetics (PK).

According a recently published report from Coherent Market Insights, the global pharmaceutical excipients market was valued at $6,557.6 million in 2018, and is expected to exhibit a CAGR of 6.9% over the forecast period (2019–2027). The market is set to surpass $11,944.6 million by 2027 the firm says.

With respect to compliance, the International Pharmaceutical Excipient Councils (IPE) governs the global pharmaceutical excipients manufacturing by providing harmonized excipient guidelines to manufacturers. IPE provide general guideline such as Good Manufacturing Practices implementation for excipient, guideline for manufacturing site selection, safety manufacturing and others.

Read More: Pharmaceutical Excipients Market Poised for Growth

Add us as a preferred source on Google

Get the latest Contract Pharma news, insights and analysis in your Google Search and AI experiences.

Add Contract Pharma as a preferred source on Google (opens in a new tab)

Keep Up With Our Content. Subscribe To Contract Pharma Newsletters

Topics